Genomic research to identify Salmonella strains that cause human disease.
Poultry used to be the usual suspect in cases of Salmonella poisoning. Today, however, most outbreaks of the illness come from fruit and vegetables that have become infected when the soil in which they grow is polluted by animal waste or non-potable water. There currently is no method of reducing the growth of Salmonella on such produce.
Poultry used to be the usual suspect in cases of Salmonella poisoning. Today, however, most outbreaks of the illness come from fruit and vegetables that have become infected when the soil in which they grow is polluted by animal waste or non-potable water. There currently is no method of reducing the growth of Salmonella on such produce.
Researchers from McGill and Laval universities will receive close to $10 million over the next four years for work that is designed to both identify and find natural solutions for the reducing the growth of the Salmonella strains that cause human disease.
This is one of two Quebec-based research projects that will receive funding from Genome Canada and Génome Québec under the program Genomics and Feeding the Future.”
“McGill’s researchers are committed to reducing foodborne disease outbreaks, which are a significant global public health threat. Genome Canada and Genome Quebec’s major investment in genomic research will lead to innovative preventive interventions for Salmonella-induced disease, and further study methods to eradicate it”, said Rosie Goldstein, Vice-Principal (Research and International Relations).
Each year, Salmonella infects some 88,000 people in Canada who consume contaminated food. And while many people suffer no ill effects, or a mild case of abdominal cramps, fever or diarrhea, others experience more serious infections, which can result in dehydration or infection travelling beyond the intestines, requiring medical attention and resulting in disability or even death. Salmonella infection is thought to cost the Canadian economy as much as $1 billion each year in medical costs, absences from work and economic losses to food companies and restaurants.
Dr. Lawrence Goodridge of McGill University and Roger C. Levesque from the Institute for Integrative Systems Biology (IBIS), Université Laval, are leading a team that is using whole genome sequencing to identify the specific Salmonella strains that cause human disease. With this knowledge, the team will develop natural biosolutions to control the presence of Salmonella in fruit and vegetables as they are growing in the field. The team will also develop new tests to rapidly and efficiently detect the presence of Salmonella on fresh produce before it is sold to consumers, as well as tools to allow public health officials to determine the source of Salmonella outbreaks when they occur, so that contaminated food can be quickly removed from grocery stores and restaurants. Their work will reduce the number of people infected with Salmonella each year, as well as the economic costs of the infection.
About Génome Québec
Since May 2000, Génome Québec has been the driving force behind the development of genomics in Québec. By supporting nearly 80 projects and 900 researchers and managing the operations of the McGill University and Génome Québec Innovation Centre, Génome Québec is helping to accelerate the discovery of new applications for genomics in strategic areas, such as personalized health care, forestry, the environment and agrifood. The funds invested by Génome Québec are provided by the Government of Québec, the Government of Canada, through Genome Canada, and private partners.